Co-op, Purification Process Development
Location: Woburn, MA
Department: Technical Development
Position Summary:
ultraimpact – Make a difference for those who need it most
Work Model:
Core Lab & Ops: This role typically requires that the majority of the work be conducted on-site and thus will be subject to certain on-site safety protocols during the pandemic.
Responsibilities:
We are seeking a motivated undergraduate/graduate student to join our AAV Purification Process Development team. The successful candidate will support laboratory and data‑driven activities that directly contribute to commercial manufacturing, process development, and clinical compatibility studies. This position offers hands‑on experience in gene therapy purification process development, exposure to GMP‑aligned development workflows, and the opportunity to learn industry‑relevant skills in various purification unit operations, clinical device compatibility, and industry relevant data analysis
- Actively contributes to programs in late-stage development to enhance AAV manufacturing technologies/capabilities and work-processes.
- Collect controlled experimental data and maintain accurate daily logs of experiments including methods, results, and conclusions.
- Conduct laboratory studies to support commercial manufacturing needs, including column and resin lifetime extension studies.
- Support development activities for AAV downstream processes, including buffer screening, filtration studies, and chromatography evaluations.
- Contribute to clinical in‑use compatibility studies, supporting material preparation, sample handling, and execution of defined protocols (as needed).
- Prepare buffers and solutions according to established procedures to support ongoing experiments and team operations.
- Support data management by compiling, organizing, and formatting process data
- Ensure high-quality, timely documentation in electronic laboratory notebooks and technical reports.
- Present scientific findings to the downstream and formulation development group or broader internal audience.
- Assist in general laboratory maintenance duties, including inventory of consumables and raw materials, buffer preparation, and routine lab maintenance/cleaning tasks.
Requirements:
- Graduate or Undergraduate student in Chemical Engineering, Biochemistry, Biology, Chemistry or a related discipline.
- This is a 6 month co-op, starting July 6, 2026 working full-time (40 hours per week) until December 18, 2026
- Strong interest in bioprocessing, AAV/gene therapy, or downstream purification.
- Experience working with chromatography and filtration systems is a plus.
- Interest in learning and working in a fast-paced environment.
- Ability to follow protocols carefully and maintain attention to detail.
- Demonstrates strong organizational and communication skills and the ability to work effectively in a collaborative team environment.
- Independently motivated and detail-oriented with good problem-solving ability.
U.S. Hourly Wage Range:
- $23.00-$30.00/hour. The estimated hourly range reflects an anticipated range for this position. The actual hourly wage offered will depend on the candidate’s school year/level.
#LI-AJ1 #LI-Onsite
The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location.
This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment.
Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at [email protected].
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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