Tessera Therapeutics

Senior Software Engineer, Applied AI

Cambridge, MA US
Terraform R Machine Learning AWS GCP Azure Docker Kubernetes
Description

Company Summary

Lila Sciences is a privately held, early-stage technology company pioneering the application of artificial intelligence to transform every aspect of the scientific method. Lila is backed by Flagship Pioneering, which brings the courage, long-term vision, and resources needed to realize unreasonable results. Join our mission-driven team and contribute to the future of science.

Our Life Sciences effort is leveraging AI and high-throughput automation for valuable therapeutic discovery and development across biological modalities.

At Lila, we are uniquely cross-functional and collaborative. We are actively reimagining the way teams work together and communicate. Therefore, we seek individuals with an inclusive mindset and a diversity of thought. Our teams thrive in unstructured and creative environments. All voices are heard because we know that experience comes in many forms, skills are transferable, and passion goes a long way.

If this sounds like an environment you’d love to work in, even if you only have some of the experience listed below, please apply.

The Role:  

We are seeking a Senior Software Engineer to join our Applied AI group and help build the next generation of our AI-driven scientific platform. In this role, you will collaborate closely with ML researchers, platform engineers, and scientists to develop agent-driven applications capable of executing complex tasks autonomously. You will also ensure seamless collaboration across diverse teams.

You’ll have the opportunity to shape a modern, production-grade system from the ground up, integrating cutting-edge AI frameworks with scalable cloud infrastructure. In our fast-paced environment, your technical expertise and creative problem-solving will push the boundaries of what’s possible in AI-driven science. This is a unique chance to be at the forefront of applied AI in scientific research. If you are passionate about building intelligent systems that can transform science, we would love to hear from you.

Key Responsibilities:

  • Lead End-to-End Implementation: Drive the technical design and implementation of AI systems, creating a scalable, extensible framework that powers iterative R&D workflows.
  • Contribute to Agentic AI Platform: Design, develop, and maintain systems leveraging large language models for intelligent decision-making. Orchestrate workflows, gather data, and refine scientific designs.
  • Architect & Implement ML Pipelines: Build and maintain end-to-end data and machine learning pipelines to facilitate a robust data environment for agentic interactions.
  • Collaborate Cross-Functionally: Partner with domain scientists, ML engineers, and product leads to integrate various technologies—ML models, data/compute infrastructure, and experimental automation tools.
  • Develop Best Practices for Agentic Systems: Establish design patterns for planning, tool selection, and evaluation, ensuring high-performance outcomes.
  • Optimize Performance & Reliability: Profile and optimize agentic workflows for throughput, fault-tolerance, and cost efficiency. Implement logging, monitoring, and alerting to ensure production readiness.
  • Champion Best Practices: Set standards for code quality, testing, and documentation. Mentor junior engineers and foster a culture of knowledge sharing.

Qualifications:

  • Bachelor’s or Master’s degreein Computer Science, Engineering, or a related field.
  • 5+ years of experiencesuccessfully building and deploying scalable software systems in production environments.
  • Cloud & DevOps Knowledge: Hands-on experience with AWS, GCP, or Azure; strong understanding of containerization (Docker/Kubernetes), infrastructure-as-code (Terraform, CloudFormation), and CI/CD pipelines.
  • Workflow Orchestration: Familiarity with modern orchestrators (Temporal, Airflow, etc.) to coordinate complex data and ML pipelines.
  • Data Engineering: Ability to design robust data flows and handle large volumes of structured/unstructured data, including performance optimization.
  • Communication & Collaboration: Proven track record of working cross-functionally with scientists, data engineers, and product teams; able to explain complex ideas to diverse audiences.

Preferred Qualifications:

  • Experience in AI/ML Pipelines: Prior work building or optimizing ML pipelines (training, evaluation, deployment); experience monitoring model performance in production.
  • Hands-On Familiarity with Latest AI Concepts: Exposure to AI technologies such as Large Language Models (LLMs), Retrieval-Augmented Generation (RAG), or agentic frameworks—and how they integrate into a software platform.
  • Domain Background: Exposure to life sciences, material sciences, or related fields.
  • Technical Leadership: Experience leading or mentoring a team and making key architecture decisions.

Working at Lila, you would have access to advanced technology in the areas of:

  • AI experimental design and simulation
  • Automated liquid handling and instrumentation
  • Generative molecular design

More About Flagship Pioneering

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

Tessera Therapeutics
Tessera Therapeutics
Biopharma Biotechnology Genetics Life Science Therapeutics

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