Pioneering Medicines Senior Director, Project Lead Metabolic Disease

What if... We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner?

Pioneering Medicines, an initiative of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability focused on conceiving and developing life-changing treatments for patients by harnessing the power of Flagship's scientific platforms and applying those innovative approaches to serious diseases with unmet medical need. Unique to Pioneering Medicines’ approach is the opportunity to combine platforms to create truly novel and potentially transformative treatments. 

About Flagship Pioneering:

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.     

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.   

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. 

 Position Summary:

The Senior Director, Project Leader at Pioneering Medicines, holds a prominent role in spearheading the development and execution of groundbreaking strategies in metabolic diseases. This position utilizes state-of-the-art scientific advancements to develop transformative therapies that expand the reach of Flagship Pioneering (FSP) platforms to a broader patient base, with a strong emphasis on collaborative efforts with pharmaceutical partners. Reporting to the VP of Program Leadership, the Senior Director is an inspirational leader with rich expertise in drug discovery, and steering cross-functional teams to develop and implement robust scientific and strategic plans from lead discovery through to initial clinical studies.  The Senior Director will play a critical role in FSP’s key innovation pipelines to drive a metabolic disease portfolio that will transform human health.  

Key Responsibilities:

• Primarily oversee all programs and strategy related to our strategic collaboration with a large pharmaceutical partner, ensuring cohesive alignment with project objectives and partnership goals, with a focus on metabolic diseases.
• Lead and manage cross-functional teams to develop and implement integrated strategies for up to 2 key programs, emphasizing the development of treatments for metabolic health from lead optimization through to initial clinical studies.
• Foster an environment of scientific rigor, proactive debate, collaborative teamwork, and accountability, nurturing a culture that balances innovation with urgent and robust R&D timelines.
• Utilize a depth of experience in metabolic diseases to anticipate challenges, identify risks, and manage resources effectively to mitigate potential issues.
• Collaborate closely with project management to develop detailed plans that include realistic timelines, budgetary controls, and resource allocations.
• Consistently communicate strategic decisions and progress to senior management at Pioneering Medicines, FSP and FSP platform companies, maintaining accountability for the overall success of the projects.

Minimum Qualifications:

• MS/PhD/MD in a scientific discipline with 8+ years of experience in drug development, with a strong focus on metabolic diseases.
• At least 3 years of leadership experience in project leadership or a related role within a cross-functional team environment.

Preferred Qualifications:

• Demonstrated leadership in a prominent role within the biopharmaceutical sector, requiring advanced interpersonal skills and an innovative, strategic approach to problem-solving.
• Capability to manage complex, multi-disciplinary projects effectively, particularly those involving metabolic diseases.
• Deep understanding of both big pharma and biotech sector cultures to identify opportunities and challenges to navigate complex multi-company collaborations.
• Strong entrepreneurial mindset with a commitment to driving novel therapeutic development in metabolic diseases.
• A flexible, fit-for-purpose, leadership style that deploys team skills to advance project goals.
• Ability to travel as required.

Values and Behaviors:

• • • A relentless focus on innovation and the rapid development of new therapeutic solutions, specifically in the treatment of metabolic diseases.
    • Entrepreneurially spirited and bold, adept at managing the uncertainties and complexities of pioneering scientific research.
    • Deeply committed to transforming patient care and improving outcomes in metabolic health.
    • Promotes a productive, energetic and collaborative environment that encourages growth, positive outcomes, and maintains the highest standards of excellence.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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