Co-op: In-Process Analytics
Location: Cambridge, MA
Department: Process Chemistry
Company Overview:
Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology & oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit www.primemedicine.com.
Fall 2026 Co-op: In-Process Analytics
Co-op Assignment Overview
Prime Medicine is seeking a Fall 2026 co-op to join our Chemistry team, with a focus on in-process analytics and purification of large RNA molecules. The successful candidate will engage in hands-on laboratory work, including UV absorbance measurements using NanoDrop, purification support, sample analysis by UPLC and mass spectrometry (MS), and endotoxin testing of synthetic guide RNA. Through this experience, the co-op will develop proficiency in oligonucleotide characterization, gain exposure to a broad range of in-process analytical techniques, contribute to data generation and documentation, and present findings at weekly team meetings. We welcome curious, collaborative problem solvers who are passionate about advancing gene-editing technologies to improve human health.
Primary Responsibilities
- Support the characterization and purification of Prime's long guide RNA (gRNA) using a suite of laboratory techniques, including ÄKTA purifier, UPLC, LC-MS, NanoDrop, and endotoxin assays
- Integrate chromatograms for gRNA crude, fraction, and final samples in accordance with Prime's SOPs to quantify full-length product purity, and tabulate results in the team's electronic lab notebook
- Learn and contribute to mass analysis of gRNA to identify the molecular weight of the full-length product and related impurities
- Assist senior scientists with buffer preparation, instrument maintenance, and the development of updated analytical methods to expand in-process analytical capacity
- Manage inventory of critical reagents for buffer preparation in support of purification and analytics operations
- Coordinate with scientists to maintain inventory records for final released materials
Required Qualifications
- Enrolled in a B.S. or M.S. program in Chemistry, Biochemistry, or a related field; basic knowledge of organic chemistry preferred
- Prior completion of general chemistry coursework and associated laboratory courses
- Strong written and oral communication skills, with excellent organizational ability and capacity to work both independently and collaboratively
- Enthusiasm for learning and contributing across multiple aspects of a research program
Preferred Qualifications
- Prior internship or co-op experience in a relevant setting
- Completion of analytical chemistry lecture and laboratory courses
- Hands-on experience in a chemistry laboratory, with familiarity with instrumentation such as HPLC, LC-MS, NanoDrop, and ÄKTA Pure
What We Offer
- A cutting-edge, mentorship-driven team with strong networking opportunities
- Full reimbursement for monthly commuting costs, including MBTA, Commuter Rail, and Bluebikes
- Access to regular seminars featuring industry experts
- Full participation in company-wide activities, including learning and development programming, social events, and more
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, skills, and education.
Please note: We are currently only considering candidates based in the greater Boston/Cambridge area.
Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.
There are more than 50,000 engineering jobs:
Subscribe to membership and unlock all jobs
Engineering Jobs
60,000+ jobs from 4,500+ well-funded companies
Updated Daily
New jobs are added every day as companies post them
Refined Search
Use filters like skill, location, etc to narrow results
Become a member
🥳🥳🥳 452 happy customers and counting...
Overall, over 80% of customers chose to renew their subscriptions after the initial sign-up.
To try it out
For active job seekers
For those who are passive looking
Cancel anytime
Frequently Asked Questions
- We prioritize job seekers as our customers, unlike bigger job sites, by charging a small fee to provide them with curated access to the best companies and up-to-date jobs. This focus allows us to deliver a more personalized and effective job search experience.
- We've got over 200,000 jobs from 15,000+ vetted companies. No fake or sleazy jobs here!
- We aggregate jobs from 15,000+ companies' career pages, so you can be sure that you're getting the most up-to-date and relevant jobs.
- We're the only job board *for* software engineers, *by* software engineers… in case you needed a reminder! We add thousands of new jobs daily and offer powerful search filters just for you. 🛠️
- Every single hour! We add 2,000-3,000 new jobs daily, so you'll always have fresh opportunities. 🚀
- Typically, job searches take 3-6 months. EchoJobs helps you spend more time applying and less time hunting. 🎯
- Check daily! We're always updating with new jobs. Set up job alerts for even quicker access. 📅
What Fellow Engineers Say