Lead Software Engineer

Location: CZE - Central Bohemian - Prague (Five)

Remote Type: Hybrid

Time Type: Full time

Job Description

Job Description

We're looking for a Lead Software Engineer with deep software development and cloud engineering skills to help build the clinical data services behind our trials.

You'll be hands-on designing and building serverless data pipelines on AWS – ingesting data from external partners, transforming and harmonizing it to meet regulatory requirements, and delivering it accurately and on time for submissions.

Ultimately accelerate the path to innovative therapies for patients.

Your Responsibilities

• Design, build, and ship production services on AWS – Python, Lambda, Step Functions, DynamoDB, S3
• Own technical design decisions end to end, from data ingestion through transformation to submission-ready delivery
• Solve hard engineering problems around scale, performance, reliability, and data correctness
• Set the engineering bar through code review, testing, and CI/CD practices; keep the platform secure and modern
• Assess the current architecture to help drive a pragmatic roadmap to reduce complexity and increase delivery speed
• Work with product managers to turn ambiguous requirements into concrete, buildable technical solutions
• Lead a small team of engineers – through design reviews, mentoring, and technical direction rather than process overhead

Must Haves

• Strong software development experience, with production Python
• AWS Lambda / Step Functions – Map States / DynamoDB / S3 / IAM 
• Experience with deployments and CI/CD pipelines 
• Solid understanding of SDLC methodologies 
• Strong problem-solving skills and the ability to work self-guided 
• Fluent in written and spoken English 

Nice to Haves

• Experience with modern data platform concepts and technologies 
• Vendor management skills
• Experience in the pharmaceutical industry
• Experience with GxP validations, particularly in GCP (Good Clinical Practices)
• Clinical data standards – CDISC SDTM, ADaM 
• Experience working in a product team 
• Databricks, PySpark, Terraform 

Why Join Us? 

• Join a team dedicated to saving and improving lives worldwide
• Collaborate with diverse colleagues to bring hope to those battling challenging diseases
• Embrace an inclusive and diverse work environment that encourages breakthrough innovation
• Equal opportunity employer committed to fostering an inclusive workplace

Our Offer

• Exciting work in a great team, global projects, international environment
• Opportunity to learn and grow professionally within the company globally
• Pension and health (Canadian Medical) contributions
• Internal reward system plus referral program
• 5 weeks annual leave, 5 sick days, 15 days of certified sick leave paid above statutory requirements annually, 40 paid hours annually for volunteering activities, 12 weeks of parental contribution
• Cafeteria for tax free benefits according to your choice (meal vouchers, sport, culture, health, travel, etc.), Multisport card, Vodafone, Raiffeisen Bank and Foodora discount programs
• Up-to-date laptop and iPhone, parking in the garage, showers, refreshments
• Competitive salary, incentive pay, and many more

Ready to take up the challenge? Apply now!
Know anybody who might be interested? Refer this job!

The date shown below is the earliest possible closing date for this posting. However, we sometimes extend the job posting period as needed, so please feel free to apply anytime you see the "Apply" button available. You may also reach out to the recruiter directly via https://www.linkedin.com/in/badumtss/

Additional location(s) Compensation Information:

Required Skills:

Amazon S3, AWS DynamoDB, AWS Lambda, AWS Step Functions, CI/CD, Cloud Computing, Identity Access Management (IAM), Python (Programming Language), Software Development, Software Development Life Cycle (SDLC)

Preferred Skills:

CDISC ADaM, Clinical Data Interchange Standards Consortium (CDISC) Standards, Databricks Platform, Good Clinical Practice (GCP), GxP Validation, Pharmaceutical Industry, PySpark, Study Data Tabulation Model (SDTM), Terraform, Vendor Management

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

10/18/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.