Sr. Research Associate, Bioanalytics

The Role:

Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology with a diverse pipeline of development programs across various diseases. As an employee you'll be part of a continually growing organization working alongside exceptional colleagues and strategic partners worldwide contributing to global health initiatives. Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience with the potential to make a significant impact on patients' lives worldwide.

Moderna's mission is to establish a leading-edge research, development, and manufacturing facility at Harwell as part of a long-term commitment to onshore mRNA vaccine production for respiratory diseases. This initiative will create a multitude of highly skilled jobs and foster collaboration with academic, NHS, and government partners across the UK. We're looking for global experts eager to join us in this endeavour, contributing to a future where access to life-saving vaccines is a reality for all.

In this position, you will support method development, validation, and sample analysis using LC/MS techniques for clinical studies. You will have the opportunity to work on a wide range of molecules such as lipids, proteins, peptides, oligos, and more in various bioanalytical matrices. The role demands a strong foundation in the regulated bioanalytical LC-MS/MS field, along with the ability to thrive in a fast-paced, scientifically stimulating environment.

Here's What You'll Do:

Your key responsibilities will be:

• Develop, qualify, and validate bioanalytical LC/MS methods for quantifying a range of molecules, including lipids and potentially proteins, peptides, amino acids, and oligos.

• Draft study plans, bioanalytical methods, and study reports.

• Conduct bioanalytical assays adhering to established protocols and SOPs, ensuring compliance with GLP/GCP guidelines.

• Support clinical studies by evaluating pharmacokinetics (PK), safety, and efficacy of Moderna’s drug candidates.

• Collaborate closely with external CROs on method development and validation.

Your responsibilities will also include:

• Performing method transfers to internal and external stakeholders for qualification and validation.

• Working closely with colleagues in Clinical Development and cross-functional teams.

• Providing mass spectrometry support to scientists in Clinical Development and other departments.

The key Moderna Mindsets you’ll need to succeed in the role:

• We obsess over learning: In this role, continuous learning and innovation are essential. You'll need to stay on the cutting edge of bioanalytical LC-MS techniques, applying new knowledge to refine and improve methodologies.

• We prioritize the platform: Your work will contribute to advancing Moderna's platform technologies, ensuring that the methods you develop align with the company's broader goals of pioneering mRNA medicines for global health impact.

Here's What You'll Bring to the Table:

• Bachelor’s degree with at least 3+ years laboratory experience or MS with 1+ years of demonstrated hands-on experience with the development and validation of bioanalytical methods using LC-MS

• Hands-on experience with sample preparation/extraction/chromatography techniques for various analytes from biological matrices such as SPE, LLE, protein precipitation using LC-MS/MS

• Ability to develop and implement methods for high throughput or (semi-)automated data analysis 

• Willingness to learn new concepts and challenge boundaries; adaptability to change 

• Organization and attention to detail; ability to handle multiple projects in a fast-paced environment 

• Strong interpersonal skills with an eagerness to work with and support colleagues in other departments 

• Proven ability to develop and work independently and to collaborate cross-functionally to accomplish goals in a timely manner

• CRO experience is preferred

• GLP and/or GCP experience preferred

• Experience using various LIMS (i.e Watson) and automated systems are preferred

• This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

Moderna offers personalized benefit programs and well-being resources as unique as our global workforce so employees can do their best work.

We recognize and appreciate your diverse needs and interests and do our best to support you at work and at home with:

• Quality healthcare and insurance benefits
• Lifestyle Spending Accounts to create your own pathway to well-being
• Free premium access to fitness, nutrition, and mindfulness classes
• Family planning and adoption benefits
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, and a discretionary year-end shutdown
• Educational resources
• Savings and investments
• Location-specific perks and extras!

The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. 

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We’re focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should

contact the Accommodations and Adjustments team at leavesandaccommodations@modernatx.com.

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