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Senior Information Security Engineer

Mayo Clinic

Hybrid
Rochester, MN
Full-time
Senior
5+ yrs
$135k–$195kPosted 2w ago

Real job — pulled straight from Mayo Clinic’s careers page · Verified July 30, 2026 · No reposts.

Job description

Mayo Clinic is hiring a Senior Information Security Engineer — a full-time, based in Rochester, MN role ($135k–$195k). Apply directly on Mayo Clinic's careers page below.

Senior Information Security Engineer - IS Mod

Location: Rochester, MN, US


Responsibilities

This Senior Information Security Engineer serves as the dedicated security design and oversight lead for Enterprise Network Segmentation within the Information Protection – Network Security (IP-NS) team, ensuring segmentation controls are architected to appropriately align with the risk profile of the assets they protect across a large, regulated healthcare environment. A strong background in network segmentation is required, including proven experience designing risk-based segmentation strategies and defining policy intent for high-risk assets. This role is a critical technical authority who partners with Product Owners, the Network Security Architect, network engineering teams, and enterprise risk stakeholders to translate asset criticality and threat modeling into control requirements. It will also validate implemented policy meets design intent; provide continued oversight of segmentation controls and drift; contribute to Tier 3 incident response; and support executive reporting on risk-reduction outcomes aligned to security control objectives. Familiarity with security monitoring, incident response, vulnerability management, and security automation is highly desirable. Ability to operate effectively in a hybrid work environment, including participation in on-site work-related events, team collaboration sessions, and key organizational activities as required.

This is a hybrid position and the incumbent must live within 100 miles of a Mayo Clinic campus.

Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.



Qualifications

Bachelor’s degree in applicable field plus five (5) years of relevant experience. Pertinent fields of study and experience include, but are not limited to, information security, computer science, information systems, engineering, or a related field.

Master’s degree in applicable field plus four (4) years of relevant experience preferred. Pertinent fields of study and experience include, but are not limited to, information security, computer science, information systems, engineering, or a related field.

One or more of the following certifications (or equivalent) are required at time of hire: CISSP, CISM, GSEC, OSCP.



Exemption Status

Exempt

Compensation Detail

$134,347.20 - $194,750.40/ year

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

Monday - Friday, 8am - 5pm

International Assignment

No

Recruiter

Ted Keefe

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Frequently asked questions

What is the salary for Senior Information Security Engineer at Mayo Clinic?

The estimated salary range for Senior Information Security Engineer at Mayo Clinic is $135,000 - $195,000 USD per year.

What skills are required for Senior Information Security Engineer at Mayo Clinic?

The required skills for Senior Information Security Engineer at Mayo Clinic include: CISSP, CISM.

What is the seniority level for Senior Information Security Engineer at Mayo Clinic?

Senior Information Security Engineer at Mayo Clinic is a Senior level position.

How do I apply for Senior Information Security Engineer at Mayo Clinic?

You can view the full description and apply for Senior Information Security Engineer at Mayo Clinic on EchoJobs: https://echojobs.io/job/mayo-clinic-senior-information-security-engineer-is-mod-l32w4.