Real job — pulled straight from Mayo Clinic’s careers page · Verified October 10, 2026 · No reposts.
Job description
Mayo Clinic is hiring a Manager, Information Security — a full-time, based in Rochester, MN role ($148k–$215k). Apply directly on Mayo Clinic's careers page below.
Manager, Information Security
Location: Rochester, MN, US
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
The Information Security Manager provides operational and tactical leadership for a defined security service, function, or team. This role translates Information Security strategy, risk requirements, and policies into effective daytoday execution; ensures reliable, compliant service delivery; and fosters a strong security culture. Operating within the Risk organization, the Manager partners with business and technology stakeholders to identify, assess, and manage information security risk in a regulated environment.
The Information Security SOC Manager, Night Shift provides operational leadership and management oversight for the Cybersecurity Operations Center (CSOC) during evening, overnight, and weekend operations. Serving as the primary management authority during assigned shifts, this role is responsible for ensuring continuous cybersecurity monitoring, incident response coordination, workforce supervision, escalation management, and operational execution. The manager leads overnight analysts and engineers, oversees staffing and shift readiness, drives employee development, and ensures adherence to established procedures, service-level agreements, regulatory requirements, and organizational security standards.
This position is accountable for the quality and effectiveness of overnight security operations, including incident escalation, investigation oversight, case management, and operational governance. The manager leverages performance metrics such as MTTD, MTTR, SLA attainment, and detection effectiveness to improve service delivery and SOC maturity while partnering with detection engineering and SOAR teams to enhance detections, playbooks, AI-enabled workflows, and operational processes. Success is measured through stable overnight operations, improved analyst performance, timely incident response, reduced case backlog, strengthened operational resilience, and reduced reliance on daytime leadership for routine after-hours decisions.
This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
Qualifications
Bachelors degree in applicable field plus eight (8) years of relevant experience. Pertinent fields of study and experience include, but are not limited to, information security, computer science, information systems, risk management, or a related field. Three years leadership/management experience (i.e. guiding technical staff, leading technical projects, or leading teams).
Master’s degree in applicable field plus six (6) years of relevant experience preferred. Pertinent fields of study and experience include, but are not limited to, information security, computer science, information systems, risk management, or a related field. Three years leadership/management experience (i.e. guiding technical staff, leading technical projects, or leading teams).
One or more of the following certifications (or equivalent) are required at time of hire: CISSP, CISM, GSEC, OSCP..
Exemption Status
Exempt
Compensation Detail
$148,137.60 - $214,760.00 / year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday, Tuesday, Thursday & Friday 9:00 PM - 6:00 AM Central Time. This is a hybrid position and must be located within 100 miles of the Rochester, MN, Phoenix, AZ, Jacksonville, FL, Eau Claire, WI, La Crosse, WI or Mankato, MN Mayo Clinic campus.
Weekend Schedule
1 weekend float day for weekend coverage
International Assignment
No
Site Description
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'. Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Maggie Kramer
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Frequently asked questions
What is the salary for Manager, Information Security at Mayo Clinic?
The estimated salary range for Manager, Information Security at Mayo Clinic is $148,000 - $215,000 USD per year.
What skills are required for Manager, Information Security at Mayo Clinic?
The required skills for Manager, Information Security at Mayo Clinic include: Cybersecurity, CISSP, CISM.
What is the seniority level for Manager, Information Security at Mayo Clinic?
Manager, Information Security at Mayo Clinic is a Manager level position.
How do I apply for Manager, Information Security at Mayo Clinic?
You can view the full description and apply for Manager, Information Security at Mayo Clinic on EchoJobs: https://echojobs.io/job/mayo-clinic-manager-information-security-p8bfj.