Real job — pulled straight from Mayo Clinic’s careers page · Verified September 25, 2026 · No reposts.
Job description
Mayo Clinic is hiring a Information Security Engineer — a full-time, based in Rochester, MN role ($102k–$143k). Apply directly on Mayo Clinic's careers page below.
Information Security Engineer
Location: Rochester, MN, US
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
The Information Security Engineer is a front-line defender in the organization’s cybersecurity operations responsible for monitoring, detecting, analyzing, and responding to cybersecurity incidents. Executes initial triage, containment, eradication, and recovery steps according to established playbooks and incident response policies. Maintains detailed records of security incidents, investigations, and remediation steps and prepares summary reports for technical and non-technical audiences. Works collaboratively with other departments, such as IT, compliance, and risk management to ensure integrated security measures are being addressed. Participates in post-incident reviews and lessons learned sessions to refine incident response processes and strengthen the organization’s security posture. Provides input to security awareness initiatives and contributes to a culture of security throughout the organization.
The Information Security Engineer independently implements, administers, and supports security solutions across enterprise systems. This role applies specialized technical knowledge to analyze security posture, design controls aligned with business requirements, and protect organizational systems and data.
This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
Qualifications
Bachelor's degree and four (4) years experience in the information security field required, OR Associates degree and 6 years' experience in the information security field. Pertinent fields of study include Computer Science, Information Systems, Engineering or related field.
Master's Degree in applicable field and two (2) years experience preferred. Pertinent fields of study include Computer Science, Information Systems, Engineering or related field.
One or more of the following certifications (or equivalent) are required at time of hire or must be obtained within two years of hire: CISSP, CISM, GSEC, OSCP.
Exemption Status
Exempt
Compensation Detail
$102,336 - $143,270 / year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday - Friday, 8am - 5pm, nights and weekends as needed with on call responsibilities. This is a hybrid position and must be located within 100 miles of: Rochester MN, La Crosse WI, Eau Claire WI, Mankato MN, Phoenix AZ or Jacksonville FL. for occasional on-site expectations.
Weekend Schedule
Nights and weekends as needed
International Assignment
No
Site Description
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'. Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Shelly Weir
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Frequently asked questions
What is the salary for Information Security Engineer at Mayo Clinic?
The estimated salary range for Information Security Engineer at Mayo Clinic is $102,000 - $143,000 USD per year.
What skills are required for Information Security Engineer at Mayo Clinic?
The required skills for Information Security Engineer at Mayo Clinic include: CISSP, CISM, Cybersecurity.
What is the seniority level for Information Security Engineer at Mayo Clinic?
Information Security Engineer at Mayo Clinic is a Mid Level / Senior level position.
How do I apply for Information Security Engineer at Mayo Clinic?
You can view the full description and apply for Information Security Engineer at Mayo Clinic on EchoJobs: https://echojobs.io/job/mayo-clinic-information-security-engineer-0xhek.