Member of Technical Staff, Gene Therapy

Department: Research

Location: San Francisco, CA

Employment Type: FullTime

Member of Technical Staff - Gene Therapy

Latch builds rigorous scientific benchmarks (benchmarks.bio) that measure how well AI agents perform real biology. Frontier AI labs and pharma use them to answer one question: can an agent handle the messy, multi-layered reasoning that real biological work demands?

Every benchmark is grounded in real experimental and clinical work, including designing experiments, interpreting data, reading clinical endpoints, and advancing compounds. Each is built by scientists who have done that work themselves.

We're roughly 100 people in San Francisco, backed by Lux Capital, Coatue, Fifty Years, Haystack, Jeff Dean, Alec Nielsen, and George Church.

We're seeking a Member of Technical Staff for Gene Therapy to lead our benchmark and define how the field measures AI in Gene Therapy.

About the role

You will be Latch's authority on gene therapy. You will own the gene therapy benchmarks on our roadmap, decide what correct work looks like in these modalities, and shape how our agents reason about them. This is a new function at Latch. You will define what it needs as much as you will execute it.

What you will do

• Author and ship the gene therapy benchmarks on our roadmap across discovery, development, translation, and long-horizon work.

• Be the scientific authority at Latch for all things gene therapy.

• Collaborate with scientists to design and run agentic drug programs in the wet lab.

• Work with CROs to run experiments and gather data that inform our benchmarks.

• Build the team lead, building a function beyond yourself.

What we look for

• 5+ years hands-on in gene therapy.

• Strong, defensible opinions about what correct work looks like.

• You seek to lead a new function and team.

Culture @ Latch

How we work. Genuinely flexible schedules— we only ask that you are extra communicative when you're coming in later than usual. We care most about hard work and output. We're respectfully opinionated; it will always be us against problems, never each other. We optimize for each other's time and bring solutions, not just problems.

Office & Perks. Waterfront office near Oracle Park, 2x free daily meals, unlimited snacks, company outings most months, and team offsites. Plus a vibrant Latch community: cycling, soccer, figure skating, boxing, run clubs, reading clubs, martial arts, music, game nights.

Compensation & Logistics

• Full-time, in-person

• Unlimited PTO (truly)

• Work Visa sponsorship

• Flexible Spending Account

• 401 contribution (no match)

• Profit Share + Ambitious Equity

• Team-wide science reading groups

• 100% covered health, dental, vision

• Relocation assistance (if applicable)

• Lunch and dinner provided every workday

• Waterfront office in China Basin, San Francisco

• Company-sponsored professional development

• Flexible working hours, so long as you maintain an onsite presence

• Best office dog: Nix

Interview Process

1. Intro Screen (30m): Recruitment Team

2. Intro Technical Screen (30m): Member of Technical Staff/CTO

3. Deeper Technical Screen (1hr): Member of Technical Staff/CTO

4. Onsite Work Trial: 2-3 days (we will take care of all accommodations)

5. Decision: 1-3 days after your interview