
Real job — pulled straight from Helix’s careers page · Verified September 17, 2026 · No reposts.
Job description
Helix is hiring a Staff Software Engineer — a full-time, remote role ($173k–$235k). Apply directly on Helix's careers page below.
Staff Software Engineer - Experience
Location: United States - Remote, Canada - Remote
Department: Engineering
Location Type: REMOTE
Employment Type: FULL_TIME
- Guide and define the strategic technical direction for the Experience platform and wider Engineering organization.
- Shape how Helix Engineering utilizes AI and advance our AI development best practices.
- Direct AI agents to automate entire engineering workflows, including codifying our prompt libraries and context frameworks.
- Design, architect, and implement software systems for our genomic applications and services, with a focus on the patient and provider experience.
- Drive complex, ambiguous projects from scoping to production with autonomy, owning the design, architecture and implementation strategy.
- Collaborate and lead cross-functional work with product managers, designers, user experience researchers, scientists, and our business leaders to drive meaningful outcomes to the business.
- Shape the engineering standards, delivery practices, and quality bars within all of Engineering.
- Serve as a dedicated technical mentor, helping grow our next generation of technical leaders.
- Champion durable solutions that eliminate entire categories of technical debt and raise reliability.
- 10+ years of equivalent professional experience as a Software Engineer, with a track record of impact at scale.
- A strong product engineering mindset, with technical decisions anchored in customer and business outcomes.
- Operates with a high degree of autonomy, identifies problems before they're escalated and drives them to resolution proactively.
- Experience implementing and a passion for driving AI adoption in engineering workflows, with a proven ability to build automated safeguards and evaluations that validate AI-generated code at scale.
- Proficiency with distributed systems built on cloud infrastructure such as AWS, GCP, or Azure.
- Deep full-stack expertise, proficient in a backend language such as Go, Java, Python, Scala, or Rust.
- Familiarity and experience developing and maintaining SPA’s on frameworks such as React, Next.js, Vue.js or similar using TypeScript/JavaScript.
- A track record of raising the technical standards and practices of engineers beyond your immediate team or department.
- Adaptable in a fast-paced startup environment where priorities may change quickly and frequently.
- Bachelor’s or Master’s degree in Computer Science or a related field.
- Familiarity with regulated software systems in any industry, such as HIPAA, ISO, or FDA.
- Experience designing and architecting event-driven architectures.
- Experience with AWS serverless infrastructure.
- Experience in the life sciences, healthcare, or genomics domain.
- Expected Helix Base:
- US: $173,000 - $234,500 USD
- CA: $173,000 - $218,000 CAD
- Expected Helix Discretionary Annual Bonus: 15% of your annual salary
- Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.
- Comprehensive Health Insurance with Date of Hire eligibility
- Above average employer paid premium coverage
- 12 weeks Helix Paid Parental Leave option
- 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
- Comprehensive Well-Being Benefits
- Flexible PTO
- Remote options for many roles and a home office stipend
- First 5 days: You’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.
- Day 5 - 30: You’ll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities.
- Day 30 - 90: You’ll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.
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Frequently asked questions
What is the salary for Staff Software Engineer at Helix?
The estimated salary range for Staff Software Engineer at Helix is $173,000 - $235,000 USD per year.
Is Staff Software Engineer at Helix a remote job?
Yes, Staff Software Engineer at Helix is a remote position. This role is open to remote candidates.
What skills are required for Staff Software Engineer at Helix?
The required skills for Staff Software Engineer at Helix include: Go, Java, Python, Scala, Rust, TypeScript, JavaScript, React, Next.js, Vue.js, AWS, GCP, Azure, AI, Machine Learning, HIPAA.
What is the seniority level for Staff Software Engineer at Helix?
Staff Software Engineer at Helix is a Staff level position.
How do I apply for Staff Software Engineer at Helix?
You can view the full description and apply for Staff Software Engineer at Helix on EchoJobs: https://echojobs.io/job/helix-staff-software-engineer-experience-ymn2u.