Key Responsibilities:
- Evaluate, integrate, and implement NGS and other nucleic acid technologies to support the molecular validation of gene therapy and genome editing projects.
- Collaborate with platform teams to identify and develop suitable sequencing and molecular assay technologies for profiling and characterizing AI generated targets.
- Build and lead a team of scientists dedicated to the development and implementation of sequencing, molecular profiling, and assay technologies across single-molecule and cellular assays to broad -omics applications.
- Establish and manage strategic partnerships with CROs, vendors, and biotechs for essential assays as needed.
- Design, plan, and execute experiments both independently and as part of a collaborative team to support research activities, project goals, and platform advancements.
- Work with the computational biology and screening teams to develop analytical methods.
- Troubleshoot and optimize experimental designs.
- Maintain detailed lab notebooks and report data and findings to the scientific team.
Basic Qualifications:
- Ph.D. in molecular biology, biochemistry, genetics, gene therapy, immunology, or a related field with a minimum of 7 years of industry experience, Masters/B.S. with 12+ years of experience.
- Extensive experience with NGS technology.
- Proven ability to build and lead a scientific team.
- Strong interest in leveraging technology in scientific research, with a track record of identifying and integrating new technology platforms into therapeutic development processes.
- In-depth understanding of the therapeutic discovery and development process, particularly for cell and gene therapies.
- Experience with quantitative analysis of on-/off-target effects and cell penetrance in gene editing and/or gene therapy.
- Proficiency in multiple of the following: phenotypic assays, gene editing, automation, high-content imaging, flow cytometry, and -omics technologies.
- Experience with automation and employing analytical, computational, and statistical methodologies to enhance development workflows.
- Ability to generate precise, reliable data and interpret it effectively.
- Strong problem-solving skills with the ability to translate scientific questions into technology and assay solutions.
- Independent, detail-oriented, and capable of managing multiple projects.
- Excellent communication and presentation skills for conveying technical information clearly.
- Ability to manage projects and influence team members effectively.
- Enthusiastic about working in a dynamic, fast-paced, and collaborative environment.
Preferred Qualifications:
- Experience in designing, developing, and executing high-quality cell profiling assays or screens using various technologies for biological research or therapeutic purposes.
- Knowledge of single-cell technologies beyond sequencing.
- Expertise in mammalian cell culture techniques.
- Experience building and managing NGS Core capabilities at scale with automationProven ability to work effectively in cross-functional team environments.
What we offer:
- A highly competitive salary, a meaningful equity ownership stake in Deep Genomics, and exceptional opportunities for learning and growth.
- Company paid benefits.
- You’ll also be joining a bright, collegial, highly-motivated group working at the intersection of two of the most exciting areas of science and technology: AI and biotechnology.
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