Principal Scientist/Associate Director, Molecular Assays and Automation

Key Responsibilities:

• Evaluate, integrate, and implement NGS and other nucleic acid technologies to support the molecular validation of gene therapy and genome editing projects.
• Collaborate with platform teams to identify and develop suitable sequencing and molecular assay technologies for profiling and characterizing AI generated targets.
• Build and lead a team of scientists dedicated to the development and implementation of sequencing, molecular profiling, and assay technologies across single-molecule and cellular assays to broad -omics applications.
• Establish and manage strategic partnerships with CROs, vendors, and biotechs for essential assays as needed.
• Design, plan, and execute experiments both independently and as part of a collaborative team to support research activities, project goals, and platform advancements.
• Work with the computational biology and screening teams to develop analytical methods.
• Troubleshoot and optimize experimental designs.
• Maintain detailed lab notebooks and report data and findings to the scientific team.

Basic Qualifications:

• Ph.D. in molecular biology, biochemistry, genetics, gene therapy, immunology, or a related field with a minimum of 7 years of industry experience, Masters/B.S. with 12+ years of experience.
•  Extensive experience with NGS technology.
• Proven ability to build and lead a scientific team.
• Strong interest in leveraging technology in scientific research, with a track record of identifying and integrating new technology platforms into therapeutic development processes.
• In-depth understanding of the therapeutic discovery and development process, particularly for cell and gene therapies.
• Experience with quantitative analysis of on-/off-target effects and cell penetrance in gene editing and/or gene therapy.
• Proficiency in multiple of the following: phenotypic assays, gene editing, automation, high-content imaging, flow cytometry, and -omics technologies.
• Experience with automation and employing analytical, computational, and statistical methodologies to enhance development workflows.
• Ability to generate precise, reliable data and interpret it effectively.
• Strong problem-solving skills with the ability to translate scientific questions into technology and assay solutions.
• Independent, detail-oriented, and capable of managing multiple projects.
• Excellent communication and presentation skills for conveying technical information clearly.
• Ability to manage projects and influence team members effectively.
• Enthusiastic about working in a dynamic, fast-paced, and collaborative environment.

Preferred Qualifications:

• Experience in designing, developing, and executing high-quality cell profiling assays or screens using various technologies for biological research or therapeutic purposes.
• Knowledge of single-cell technologies beyond sequencing.
• Expertise in mammalian cell culture techniques.
• Experience building and managing NGS Core capabilities at scale with automationProven ability to work effectively in cross-functional team environments.

What we offer:

• A highly competitive salary, a meaningful equity ownership stake in Deep Genomics, and exceptional opportunities for learning and growth.
• Company paid benefits.
• You’ll also be joining a bright, collegial, highly-motivated group working at the intersection of two of the most exciting areas of science and technology: AI and biotechnology.