
Real job — pulled straight from Cellares’s careers page · Verified July 12, 2026 · No reposts.
Job description
Cellares is hiring a Principal Enterprise Data Architect — a full-time, based in South San Francisco, CA role. Apply directly on Cellares's careers page below.
Principal Enterprise Data Architect
Team: IT
Location: South San Francisco, CA
Commitment: Full Time
Workplace Type: onsite
Cellares is building a next-generation Integrated Digital Manufacturing Operations (IDMO) platform to enable scalable, GMP-compliant cell therapy manufacturing. As part of this transformation, we are establishing a modern enterprise data foundation powered by Databricks to unify data across engineering, manufacturing, quality, supply chain, finance and commercial systems.
We are seeking a Principal Enterprise Data Architect, a highly hands-on individual contributor who will design, build, and operationalize our enterprise data platform from the ground up.
This is a multidisciplinary role and this individual will play a critical role in enabling real-time decision-making, data governance, and AI readiness across the enterprise. This role is a startup-style builder (90% hands-on) and will evolve into a foundational leader for scaling data capabilities, including alignment with our Global Capability Center (GCC).
Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.
Responsibilities
- Architect and implement Databricks Lakehouse architecture
- Build end-to-end ETL/ELT pipelines
- Define canonical data models and scalable patterns
- Integrate SAP S/4HANA, Tulip MES, LabVantage LIMS, Salesforce, and engineering systems
- Align with API-first/event-driven architecture (MuleSoft / Workato)
- Define data glossary, lineage, and quality frameworks
- Implement Unity Catalog and governance aligned to GMP/21 CFR Part 11
- Prepare datasets for analytics and AI/ML use cases
- Support structured and unstructured data processing
- Evaluate and implement BI tools (Sigma, Looker, Tableau)
- Enable self-service analytics with governance
- Build pipelines using Python, SQL, Spark
- Establish reusable frameworks
- Partner with engineering, manufacturing, quality, finance and software teams
- Translate business needs into data solutions
Requirements
- Bachelor’s or Master’s degree in Engineering, Life Sciences, Information Systems, or related field
- 10+ years in data architecture/data engineering
- Strong Databricks/Spark experience
- Experience building data platforms from scratch
- Integration with ERP/MES/LIMS/CRM systems
- Azure cloud experience
- Self-awareness, integrity, authenticity, and a growth/entrepreneurial mindset
Get Principal Enterprise Data Architect jobs like this→
New roles from thousands of companies land hourly, straight from their careers pages. Get the freshest matches by email so you never miss one.
Email me new jobsSimilar jobs
Frequently asked questions
What skills are required for Principal Enterprise Data Architect at Cellares?
The required skills for Principal Enterprise Data Architect at Cellares include: Databricks, Spark, Python, SQL, Azure, Salesforce, Looker, Tableau, ETL, API, Machine Learning, AI, ERP, CRM.
What is the seniority level for Principal Enterprise Data Architect at Cellares?
Principal Enterprise Data Architect at Cellares is a Principal level position.
How do I apply for Principal Enterprise Data Architect at Cellares?
You can view the full description and apply for Principal Enterprise Data Architect at Cellares on EchoJobs: https://echojobs.io/job/cellares-principal-enterprise-data-architect-bqdkg.

