Description
WHO WE ARE
Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We seek a talented and experienced Senior Research Associate II - Preclinical Development to work onsite based in our South San Francisco office.
ArsenalBio’s mission and purpose are very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.
Driven by a collective of diverse experts across multi-scientific disciplines and clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.
This means you’ll have the opportunity to work with the best talent in the field of cell therapy and be part of ONE TEAM, which advances therapies for patients who need it most.
WHAT YOU’LL DO
- Independently plan, execute, analyze, and report on experiments to support the preclinical development of novel T cell therapy products across multiple pipeline programs
- Perform in vitro cell-based functional assays (cytotoxicity, cytokine, proliferation, etc.) for CAR T cell therapeutic candidate selection
- Design, execute, and analyze flow cytometry experiments for CAR T cell product characterization
- Support engineered T cell production activities (e.x. gene editing, T cell culture, cryopreservation, cell thawing)
- Culture both engineered primary T cell and suspension/adherent cell lines
- Support IND-enabling preclinical studies
- Assist effectively on cross-functional activities for project teams, including hand-offs, data analysis, and presenting at project meetings
- Maintain an up-to-date and detailed electronic lab notebook
- Coordinate tasks across multiple projects and teams, demonstrating prioritization and planning
- Execute and interpret experiments effectively in line with project timelines and goals
WHO YOU ARE
- Masters in Cell or Molecular Biology, Biological Sciences or a related field with 2+ years industry experience. Or, Bachelors in a related field with 4+ years industry experience; knowledge of CAR T cell therapy is a plus; industry experience is preferred
- Excellent mammalian cell culture skills are required
- Experience with multi-colour flow cytometry, panel design, and data analysis is required, and expertise in this area is highly preferred
- Experience with immunological assays, such as cytokine/chemokine analysis (e.x. ELISA or Luminex) and cytotoxicity, is highly preferred
- Proficiency using data analysis tools such as FlowJo and GraphPad Prism is highly preferred
- Experience mentoring/supervising junior research technicians is preferred
- Ability to quickly adapt and learn new skills for changing research priorities
- Demonstrated ability to work as a team player in a collaborative environment and coordinate tasks across multiple projects to meet deadlines
- Strong organizational skills, record keeping, and interpersonal communication skills (verbal and written)
- Flexible mind with the ability to think outside the box, creative approach to problem-solving
- Willingness to accept responsibilities outside of initial job description
- Passion for your work
- A positive attitude
- Experience with primary T cell culture
- Experience with CRISPR gene editing and cell engineering workflows
- Experience with Incucyte live cell imager
- Experience with semi-automated pipetting workflows (e.x. Integra VIAFLO)
Preferred Skills:
BENEFITS AND PAY
ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge.
Our people-first culture cultivates a deep respect for humanity, not only in those we serve but also in one another. We take pride in being part of a company that values and celebrates diversity—in experiences, ideas, and interests. We are empowered in an environment that embraces unity and inclusivity, fostering a sense of belonging and mutual respect.
We provide powerful tools to empower our employees to take charge of their career paths and reach their full potential. At ArsenalBio, we believe in investing in our employees' well-being—both professionally and personally—because our people are our most valuable asset. Our essential team members bring exceptional expertise in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software, and other fields to turn the possibilities of tomorrow into the realities of today.
We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.
We are an equal opportunity employer and deeply value diversity within our company. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability.
The estimated base salary for the preferred primary location of the San Francisco Bay area ranges from $96,700 – $118,500. Salary ranges for other locations may vary. Base pay offered may vary based on job-related knowledge, experience, education, and location. Beyond these considerations, we are committed to pay equity and consider the internal equity of our current employees when making any final offers.
To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias or to ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.
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