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Principal Systems Engineer, Clinical Computation Platform

Amgen

On-site
Hyderabad, India
Full-time
Principal
13+ yrs
Salary not listedPosted 1mo ago

Real job — pulled straight from Amgen’s careers page · Verified July 14, 2026 · No reposts.

Job description

Amgen is hiring a Principal Systems Engineer, Clinical Computation Platform — a full-time, based in Hyderabad, India role. Apply directly on Amgen's careers page below.

Principal Systems Engineer – Clinical Computation Platform

Location: India - Hyderabad

Remote Type: On Site

Time Type: Full time

Job Description

Career Category

Clinical

Job Description

ABOUT AMGEN 

Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Amgen helped establish the biotechnology industry more than 40 years ago and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today. 

  

ABOUT THE ROLE 

Role Description: 

The role is responsible for the design, integration, and management of complex systems that encompass both hardware and software components into the organization’s cloud infrastructure. This individual will be responsible for all activities related to handling and supporting the Business and platforms including system administration, as well as incorporating new technologies under the challenge of a sophisticated and constantly evolving technology landscape. This role involves ensuring that all parts of a system work together seamlessly to meet the organization’s requirements. 

Roles & Responsibilities:  

  • Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization 

  • Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines 

  • Support selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered 

  • Develop and design systems architecture, ensuring that it meets both current and future needs of the organization 

  • Integrate hardware and software components into a cohesive system that meets functional and performance requirements 

  • Perform system testing and validation to ensure all components function correctly and efficiently 

  • Optimize system performance and troubleshoot any issues that arise during system operation 

  • Create and maintain comprehensive documentation of systems design, configurations, and procedures 

  • Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems 

  • Monitor and maintain systems to ensure they continue to operate effectively and efficiently 

  • Implement automation tools and processes to improve the efficiency and reliability of the system 

  • Conduct training and workshops for business teams to share best practices in the industry. 

Basic Qualifications and Experience: 

  • Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science, IT or related field

Functional Skills: 

Must-Have Skills: 

  • Experience in cloud platforms including AWS 

  • Experience with container technologies like Docker and Kubernetes 

  • Hands-on experience with computerized systems including troubleshooting, reliability, and performance improvements 

  • Experience with translating business requirements to technical requirements and recommend solutions for automation 

  • Proficiency in programming languages including R,  Python 

  • Experience and strong knowledge of POSIT Tools and Services 

  • Strong understanding of software development methodologies, including Agile and Scrum 

Good-to-Have Skills: 

  • Experience with DevOps tools and practices 

  • Strong understanding of systems engineering processes and methodologies 

  • Experience with systems integration and validation 

  • Knowledge of Clinical Development domain 

Professional Certifications: 

  • Scaled Agile Framework (SAFe) for Teams (preferred) 

Soft Skills: 

  • Excellent analytical and troubleshooting skills 

  • Strong verbal and written communication skills 

  • Ability to work effectively with global, virtual teams 

  • High degree of initiative and self-motivation 

  • Ability to manage multiple priorities successfully 

  • Team-oriented, with a focus on achieving team goals 

  • Strong presentation and public speaking skills 

 

Shift Information: 

This position requires you to work a later shift and may be assigned a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as required based on business requirements. 

EQUAL OPPORTUNITY STATEMENT 

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. 

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Frequently asked questions

What skills are required for Principal Systems Engineer, Clinical Computation Platform at Amgen?

The required skills for Principal Systems Engineer, Clinical Computation Platform at Amgen include: AWS, Docker, Kubernetes, R, Python, Agile, Scrum, DevOps.

What is the seniority level for Principal Systems Engineer, Clinical Computation Platform at Amgen?

Principal Systems Engineer, Clinical Computation Platform at Amgen is a Principal level position.

How do I apply for Principal Systems Engineer, Clinical Computation Platform at Amgen?

You can view the full description and apply for Principal Systems Engineer, Clinical Computation Platform at Amgen on EchoJobs: https://echojobs.io/job/amgen-principal-systems-engineer-clinical-computation-platform-7dw49.