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Grail

Senior / Staff Engineer, Technical Operations #3640

Menlo Park, CA
USD 127k - 159k
Python R
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Description
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit www.grail.com.

GRAIL is seeking a Sr. Engineer in Technical Operations in our Menlo Park facility. The ideal candidate is a team player with hands-on experience developing and implementing validation plans for laboratory and/or manufacturing equipment and a willingness to lead and teach others. The candidate will be encouraged to think outside of the box to creatively solve problems related to the management and execution of NGS-based workflows. They will work collaboratively across organizational functions and execute experiments individually and as a team. The candidate will be instrumental in implementing process improvements, developing documentation, and carrying out verification and support functions for operations within GRAIL laboratories.

Responsibilities:

  • Act as the Technical Operations SME for equipment, equipment performance specifications, and processes in use by the Lab Operations team
  • Develop expertise in automation, software, performance data, and specifications related to instrumentation, equipment, and consumables used in the execution of Grail’s commercial assay(s)
  • Coordinate across Technical Operations to develop and execute business programs supporting Verification/Validation, Improvements, and Investigations.
  • Serve as the primary project coordinator for Technical Operations automation improvements at the MPK facility, coordinating with the RTP site.
  • Contribute to quality, optimization, and technology transfer projects
  • Independently design, conduct and analyze data from experiments to support automated NGS-based assays.
  • Lead and contribute to investigation teams in troubleshooting and root cause analysis across operational functions and workflows
  • Ensure laboratory activities are performed and documented following regulatory and study requirements (GLPSOW/CAP/CLIA/FDA)

Preferred qualifications:

  • Minimum of B.Sc/M.S. in BioEngineering, Molecular Biology, Biochemistry, Automation Engineering, or a related field or equivalent
  • 6+ years of Automation-related experience
  • 2+ years of experience in the development or support of Next Generation Sequencing assays and workflow
  • Experience working in a regulated environment under CAP/CLIA and/or FDA, including documentation, change management/control, and non-conformance programs
  • Expertise in manufacturing or automation of clinical diagnostics, medical devices, or equivalent
  • Demonstrated Technical leadership, self-direction, and willingness to teach others and learn new techniques.
  • Good planning, prioritization, problem-solving, and organizational skills
  • Data analysis using tools such as JMP, or proficiency with R or Python
  • Effective written and verbal communication skills (fluency in English) as well as strong interpersonal, negotiation, and influencing skills
  • Experience with GSuite, Jira, and/or Confluence
The expected, full-time, annual base pay scale for this position is $127,000 - $159,000.  Actual base pay will consider skills, experience, and location.

Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.

In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.

GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.
Grail
Grail
Biotechnology Health Care Health Diagnostics Medical Medical Device

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