Staff Engineer, Infrastructure

About Atomwise

Atomwise is a TechBio company leveraging AI/ML to revolutionize small molecule drug discovery. The Atomwise team invented the use of deep learning for structure-based drug design; a core technology of Atomwise’s best-in-class AI discovery and optimization engine, which is differentiated by its ability to find and optimize novel chemical matter. The company’s belief is that structurally novel chemical matter increases the likelihood of developing first-in-class and best-in-class medicines that have the potential to transform patient care. 

Atomwise has extensively tested its discovery and optimization engine, delivering hit ID success in over 230 academic and collaboration projects to date that cover a wide breadth of protein classes and numerous “hard-to-drug” targets. Atomwise is building a wholly-owned pipeline of small molecule drug candidates and plans to file an IND application this year for its lead candidate, a novel allosteric TYK2 inhibitor with first-in-class and best-in-class potential. 

The company has raised over $174 million from leading venture capital firms to advance its vision to invent a better way to discover and develop new medicines to help patients. 

About the role

Our Engineering Team is a small, cohesive, remote team that owns the drug discovery platform.  As a Staff Infrastructure Engineer, you will manage a complex network of systems making heavy use of AWS, Terraform, and Kubernetes, scaling to thousands of nodes, and petabytes of data.

Key Responsibilities

• Own significant portions of the infrastructure stack and lead efforts to make strategic improvements.
• Collaborate with other engineering leaders to align infrastructure strategies with overall business goals.
• Evaluate and recommend new tools and methodologies.
• Implement and optimize CI/CD pipelines for efficiency and reliability.
• Continuously improve deployment and operational processes.
• Collaborate with security and compliance teams to ensure infrastructure meets industry standards.
• Work closely with software architects to influence overall system design.

Required Qualifications

• 5+ years of experience in DevOps or infrastructure roles.
• Expertise in Bash, Python and relevant frameworks
• Expertise in containerization and orchestration tools (e.g. Kubernetes, Docker)
• Expertise in cloud platforms (e.g., AWS, Azure).
• In depth knowledge of Infrastructure as code (e.g. Terraform, Chef, Ansible)
• Strong understanding of security and compliance requirements.

Preferred Qualifications

• Experience with workflow systems - e.g. Flyte, Argo, MLFlow

Compensation & benefits

• Competitive salary, commensurate with experience
• Stock compensation plan – you’ll be an Atomwise co-owner
• Platinum health, dental, and vision benefits for you and your dependents
• 401(k) retirement plan with generous company match (up to 4%)
• Flexible paid time off (PTO), 13 paid holidays, and wellness breaks for employees to spend time with their loved ones and recharge
• Health Savings and Flexible Spending Account options to help save money on healthcare, daycare, and commuting
• Employee Assistance Program (EAP) and Pet Insurance
• Funding for professional development and conference attendance
• Flexible work schedule
• Generous paid parental leave

Atomwise is an equal opportunity employer and strives to foster an inclusive workplace.  Our mission is to develop better medicines faster, and we know that we need a diverse team to develop medicines that serve diverse populations.  Accordingly, Atomwise does not make any employment decisions (including but not limited to, hiring, compensation, and promotions) on the basis of race, religion, color, national origin, gender, gender identity, sexual orientation, age, veteran status, disability status, or any other characteristics protected by applicable federal, state, and local law.

We strongly encourage people of diverse backgrounds and perspectives to apply.

*Pay range for this role is between $145,000 - $183,000*